![]() ![]() The detected p.F79=SNP has a highly negative effect on EN and BW in Japanese quail. The p.F79=SNP was largely detected in the WT line than the other two lines. Association analyses indicated a significant ( P < 0.05) relation of this SNP with egg number (EN) and bird weight (BW) in the analyzed populations, in which the birds with AG genotype had lower EN and BW than those with AA genotype. ![]() In this locus, a novel single nucleotide polymorphism (SNP) was detected in which “A” was substituted with “G” at 81 position with a silent effect (p.F79=SNP) on IGF2 protein. ResultsĪll the genotyped regions exerted no heterogeneity in their sequences with one exception detected in the exon 2. A total of 240 female birds with an equal number of three Japanese quail populations (Brown or BR, Black or BL, and White or WT) were included in this study. ![]() This study was conducted to genotype the coding regions of the IGF2 gene in Japanese quail ( Coturnix japonica) using PCR-SSCP-sequencing, and to assess the possible association of the polymorphism of these regions with the main egg production traits. It is involved in several insulin-like growth-regulating and mitogenic activities. Insulin-like growth factor 2 ( IGF2) is one of three hormones that share high structural similarity to insulin. ![]()
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January 2023
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